Hemodynamic Monitoring Systems Market Size – Drivers, Restraints, Opportunities, and Challenges

Hemodynamic Monitoring Systems MarketThe global hemodynamic monitoring systems market is growing due to technological advancement in hemodynamic monitoring systems, such as minimally invasive and noninvasive technologies. The minimally invasive and noninvasive technologies are preferred, in order to reduce infection associated diseases, decrease pain, and increase comfort of the patient. The massive unexplored market in the hemodynamic monitoring systems industry of the developing economies is creating abundant opportunities for the growth of the global hemodynamic monitoring systems market.

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Hemodynamic monitoring is the continuous movement of blood and pressure exerted in the veins, arteries, and heart. Hemodynamic monitoring systems are used to monitor oxygenation of tissue and organ, blood pressure, and cardiac output. It is also used to evaluate effectiveness of the cardiovascular function. These tests are performed to monitor loss of cardiac functions, such as cardiomyopathy, congestive heart failure and myocardial infarction, decreased urine output, decreased cardiac output, and gastrointestinal bleeding.

On the basis of type, the global hemodynamic patient monitoring systems market can be categorized as minimally invasive systems, invasive hemodynamic monitoring systems, and noninvasive systems. Invasive hemodynamic monitoring systems leads the global hemodynamic monitoring systems market in terms of market size, due to identification, early detection, and treatment of life threatening diseases; whereas, the market share minimally invasive hemodynamic monitoring systems is expected to grow at the fastest rate in the coming years. In addition, on the basis of end user, the global hemodynamic patient monitoring systems market can be categorized as hospitals, catheterization laboratories, and home and ambulatory sites. Hospitals lead the global hemodynamic monitoring systems market in terms of market size, and are expected to grow at the fastest rate in the coming years.

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Some of the companies operating in the global hemodynamic monitoring systems market are Edward Lifesciences Corporation, Pulsion Medical Systems Se, Cheetah Medical Inc., HEMO Sapiens Inc., Deltex Medical Group PLC, ICU Medical Inc., Tensys Medical Inc. Osypka Medical GMBH, Lidco Group PLC and Schwarzer Cardiotek GmbH.


Endometrial Cancer Treatment Market Pipeline Analysis, Share and Forecast to 2023

Endometrial Cancer Treatment Market

The global endometrial cancer treatment market is expected to witness growth due to unmet need of treatment, technological advancement in cancer therapeutics and diagnostic test, rising prevalence of cancer, and sedentary lifestyle of women. In addition, increasing awareness about the uterine diseases and the available therapies and increasing healthcare expenditure is also driving the growth of global endometrial cancer treatment market.

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The pharmaceutical companies are actively involved in the endometrial cancer research and development. AEterna Zentaris, Inc., is developing Zoptrex (zoptarelin doxorubicin), a Phase III clinical trial drug candidate for the treatment of endometrial cancer. In October 2016, the company entered into licensing agreement with Specialized Therapeutics Asia, a biopharmaceutical company, for the marketing of zoptarelin doxorubicin in Australia and New Zealand.

Endometrial cancer is an abnormal growth of uterus, in which inner lining of the uterus known as endometrium got affected. The American Cancer Society estimated that in year 2016, about 60,050 new cases of endometrial cancer would be diagnosed in the U.S. and about 10,470 women would die from cancers of the uterine body. The sign and symptoms of endometrial cancer is abnormal vaginal bleeding. It is most often diagnosed by pelvic ultrasound and transvaginal ultrasound. An endometrial biopsy is also preferred in postmenopausal women with endometrial cancer.

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Some of the key players operating in the global market are Bristol-Myers Squibb Company, Merck & Co., Inc., Ariad Pharmaceuticals Inc., GlaxoSmithKline plc, Novartis AG, Sanofi, Eisai Co., Ltd., Exelixis, Inc., F. Hoffmann-La Roche AG, and Abbott Laboratories.

Immune Checkpoint Inhibitors Market Analysis, Size & Forecast to 2023

Immune Checkpoint Inhibitors Market

The global immune checkpoint inhibitors market is expected to witness significant growth as these are proven to be more effective therapy in shrinking tumor in higher proportion of patients, as compared to other immunotherapies. Immune checkpoint inhibitors are applicable to a wider range of tumor types such as advanced or metastatic non-small cell lung cancer, renal cancer and melanoma. These inhibitors lower the rate of severe toxicities and immune-mediated side-effects. These are also convenient to administer and yield a good response rate of any single-agent immunotherapy.

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The pharmaceutical companies are actively involved in the research and development of drug for immune checkpoint inhibitors. The pipeline of immune checkpoint inhibitors is rich with more than 50 drugs. In November 2016, Bristol-Myers Squibb Company and Infinity Pharmaceuticals collaborated to check the efficacy of combination of Opdivo (a PD-1 inhibitor monoclonal antibody) and IPI-549 (a phosphoinositide-3-kinase gamma inhibitor) in patients with advanced solid tumors.

Immune checkpoint inhibitors are showing good efficacy with PD-1 and PD-L1 inhibitors and CTLA-4 inhibitors. Yervoy, an anti-CTLA-4 product of Bristol-Myers Squibb Company got approved in the year 2011. The increased use of combination therapy of PD-1 and PD-L1 inhibitors represent a new signal of immunotherapeutics, which is expected to alter the standard of care for cancer across the globe. However, the development of effective immunotherapy presents some challenges due to complex pathophysiology of cancer and difficulty in managing treatment related toxic effects, which is expected to hamper the growth of the global market to some extent.

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Some of the key players operating in the global market are Merck & Co., Inc., Bristol-Myers Squibb Company, AstraZeneca plc, Pfizer Inc., F. Hoffmann-La Roche AG, Novartis AG, Regeneron Pharmaceuticals, Inc., Ono Pharmaceutical Co., Ltd., and TG Therapeutics, Inc.

Blood Collection Market – Trends, Analysis and Research Report, 2023

Blood Collection Market

The global blood collection market is witnessing considerable growth due to increasing geriatric population, increasing number of accidental cases and growing surgical procedures. Moreover, growing prevalence of chronic diseases including cancer, cardiovascular disease, infectious diseases, autoimmune diseases, diabetes mellitus, and infectious diseases is supporting the growth of the market. Based on product type, the blood collection needle and syringe segment lead the market. The increasing demand of needle and syringe for blood collection across the globe, owing to their easy availability and ease of use, is driving the growth of this segment. In addition, rising initiatives undertaken by government associations to boost awareness about blood donations and advanced features of blood collection products are also supporting to the growth of this market.

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The use of RFID technology in blood banks and transfusion medicine has the potential to improve operational efficiency. It helps in providing patient safety at point of care by automatically identifying, reconciling, and tracking blood products throughout the blood supply chain. The increasing use of radiofrequency identification (RFID) and needle free devices is expected to create opportunities for the manufacturers of blood collection products. However, risk associated with blood transfusions and growing needlestick injuries are the key factors hampering the growth of the global market.

Geographically, North America has been the largest market for blood collection, owing to increased awareness, established healthcare industry, and easy increasing prevalence of infectious and non-infectious diseases in the region. The U.S. contributed largest revenue to the North American as well as global blood collection market. The presence of large number of diagnostic laboratories and hospitals, and increasing prevalence of people with blood disorders are the key growth driving factors for the U.S. blood collection market.

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The key players operating in the global blood collection market are Abbott Laboratories Inc., Becton, Dickinson and Company, Terumo Corporation, Sarstedt AG & Co., Nipro Medical Corporation, Qiagen, Haemonetics Corporation, Greiner Holding AG and F.L. Medical SRL.

Cartilage Repair Market Size, Share and Forecast to 2023

Cartilage Repair MarketThe global cartilage repair market is witnessing considerable growth due to increasing geriatric population, increasing obesity, increasing healthcare expenditure, and growing sports related injuries. Moreover, increase in innovative product launches and growth of medical tourism leading to awareness about the cartilage treatment modalities across the globe is supporting the growth of the market. Based on the treatment modalities, cell-based approaches segment is expected to grow at the fastest rate during the forecast period, due to long term results of this treatment.

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Obesity is a serious health concern in the U.S. The increasing prevalence of obesity is driving the growth of the cartilage repair market in the U.S. According to CDC, during 2011-2012, 35.1% of adult aged 20 years or above were obese. In addition, as published by the Organization for Economic Cooperation and Development (OECD) in the year 2014, the obesity rate in Germany increased from 11.5% in 1999 to 14.7% in 2009. This increase in obesity rate leads to increase in demand for liposuction procedures, which is further accelerating the market growth.

Europe has been the second largest market for cartilage repair, where the market is driven by the increasing demand for cell-based approaches, increasing healthcare expenditure and launch of novel products. In 2015, Germany led the European cartilage repair market and it is also expected to grow at the fastest rate in Europe, during the forecast period. Globally, the cartilage repair market is expected to witness the fastest growth in Asia-Pacific during the forecast period, attributed to the increasing per capita income leading to improved standard of living, increasing healthcare spending, growing demand for better quality medical care, and awareness about cartilage repair treatments in the region.

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The key players operating in the global cartilage repair market are Zimmer Biomet Holdings, Inc., Johnson & Johnson, Vericel Corporation, Smith & Nephew PLC, Osiris Therapeutics, Inc., RTI Surgical, Conmed Linvatec, B. Braun Melsungen AG, Anika Therapeutics S. R. L.  and Arthrex, Inc.

Care Management Solutions Market Analysis, Trends and Demand,

Care Management Solutions Market

The growth of global care management solutions market is led by growing geriatric population, increasing demand for quality of care and increasing government initiatives to promote patient-centric care, increasing prevalence of chronic diseases, advancing IT and big data capabilities and growing medical tourism. Initiatives to move the burden of threat from healthcare payers to providers and need to reduce healthcare cost are further expected to boost the demand of these solutions. The fastest increase in demand of care management solutions during the forecast period is expected to be witnessed in chronic care management segment, due to increasing demand of improving quality of care and save time for providers. Based on component, software segment leads the global market in terms of size, due to technological advancement in IT solution, growth of cloud computing and increased access of internet across the globe.

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Increasing prevalence of chronic diseases is driving the growth of the global care management solutions market due to increasing demand for quality of care. The prevalence of chronic diseases, such as heart disease, cancer, stroke and respiratory disease, are increasing due to the alteration in lifestyle and lack of access to preventive care. According to the Centers for Disease Control and Prevention (CDC), approximately 117 million people in the U.S. had one or more chronic health conditions in 2012.

Care management solution is an integrated healthcare solution that offers products and services to improve quality of care of patients. It identifies the need of care, manage care, monitor results and outcomes, assess patient’s needs, and establish the appropriate care plan to support their needs. It combines analytics, data integration, and coordination of care capabilities into a single solution.

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The key players operating in the global market are Allscripts Healthcare solutions Inc., Cerner Corporation, Epic Corporation, Inc., Wellentive Inc., I2I System Inc, and IBM Corporation.

Multiple Myeloma Therapeutics Pipeline – Patent, Collaboration and Other Developments

Multiple Myeloma (MM) Therapeutics Pipeline

The multiple myeloma therapeutics pipeline is expected to witness considerable growth in the coming year due to high prevalence of the disease. The growth of multiple myeloma therapeutics pipeline is assisted by targeted therapy and new effective treatment. Also, increased awareness among the population about the various cancer treatments has further fueled the growth of the therapeutics pipeline. Increasing healthcare expenditure and technological advancements are supporting the growth of the therapeutics pipeline for multiple myeloma. An increasing demand for safe and effective medications is also driving the growth of the multiple myeloma therapeutics pipeline. Many government initiatives such as increased funding, designations and grants for speeding up the drug development process has also supported the growth of the therapeutics pipeline.

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The National Cancer Institute, which is a part of the U.S. National Institutes of Health, defines multiple myeloma as a cancer that is formed by malignant plasma cells. Normal plasma cells are found in the bone marrow as an important part of the immune system. The immune system is made up of several types of cells that work together to fight infections and other diseases. Lymphocytes (lymph cells) are the main cell types of the human immune system and the major types of lymphocytes are T cells and B cells. When B cells respond to an infection, they mature and change into plasma cells. Plasma cells make the antibodies (also known as immunoglobulins) that help the body attack and kill germs. Lymphocytes are present in many areas of the body, such as lymph nodes, bone marrow, intestines, and the bloodstream. Plasma cells, however, are mainly found in the bone marrow. Bone marrow is the soft tissue found inside some hollow bones. In addition to plasma cells, the bone marrow has those cells that make the different normal blood cells.

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Some of the companies having a pipeline of myeloma therapeutics include Celgene Corporation, Bristol-Myers Squibb, Abbvie, Inc., Novartis AG, F. Hoffman La Roche AG, Amgen, Inc., Karyopharm Therapeutics, Inc., Array BioPharma, and Takeda Pharmaceutical Company Limited.

Cluster Headache Therapeutics Pipeline Analysis 2017 – Collaboration and Other Developments

Cluster Headache Therapeutics Pipeline Analysis

Rapidly increasing pace of life, change in lifestyle, higher stress levels, etc., are few of the major factors to which the increasing prevalence of cluster headache scan be attributed. Further, unhealthy dietary intake, smoking, alcoholconsumption and growing levels of pollutionare few other factors which are expected to fuel the incidence of cluster headache problem. The Therapeutic pipeline of cluster headache is expected to grow in future with the participation of various pharmaceutical companies that are focusing on developing novel drugs for curing the problem of cluster headache. As per WHO, problem of cluster headache is more common in men, as compared to women, and mostly in people in the age group of 20 to 40 years. According to a recently published NCBI paper, one of every 1,000 adults in the U.S. experiences the problem of cluster headache. In spite of the problem of cluster headache being very common, it has mostly been under-recognized and has been overlooked.

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Cluster headache, also called ashistamine headache, is a primary headachedisorder of the nervous system, and is a headache of constant nature, experienced over a prolonged period of time, occurring mostly at night during sleep. According to the studies conducted by International Headache society (IHS), during cluster headache the patient experiences very severe pain, which occurs for duration of 15 to 180 minutes, once a day. Lacrimation, facial sweating, eyelid edema, restlessness, runny nose, rhinorrhea, ptosis, one-sided pain, nasal congestion, miosis & conjunctivitis, are few of the symptoms ofdiagnosing cluster headache.

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Some of the companies having a pipeline of cluster headache therapeutics include Eliy-lilly& Company, Teva pharmaceuticals industries Ltd, Winston laboratories,Gilead Sciences, Inc., Galapagos NV, Astellas Pharma, Abbvie, Inc., Bexalta US, Inc., Optimer pharmaceutical LLC.

Asthma Therapeutics Pipeline Analysis 2017

Asthma Therapeutics Pipeline Analysis

The pipeline for asthma therapeutics is expected to experience a positive trend in the future, the increase is mainly attributable to decreasing air quality. The prevalence of asthma is increasing globally due to the factors including environmental factors, genetic factors, air pollution, less physical activity and smoking. These factors contribute immensely in driving the pipeline analysis for asthma. According to World Health Organization, around 235 million people suffered from asthma, in 2013. Asthma related deaths occurs more commonly in low and lower middle income countries. Asthma is a very common disease and the treatment options available for the same are expensive. It has been also notes that the disease is more prevalent in women as compared to men.

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Asthma is a chronic disease that involves inflammation of bronchial tubes. Bronchial tubes allow air to pass through the lungs and when the lungs get inflamed muscles tend to become stiff, resulting in various symptoms that might be experienced by the patient. The inflammation of bronchial tubes affects the air passage which results in the occurrence of symptoms including breath shortening, wheezing, coughing and chest congestion. These symptoms are usually very active during physical activities such as exercising, walking and running. People with family history of asthma have more chances to develop asthma. There is no cure of asthma, but various treatment options can help to improve the quality of life of patient. Along with the common symptoms of asthma, pattern of symptoms occurrence is also important during diagnosis. Patterns usually include during exercise, during particular season and morning or night. Asthma can be diagnosed by analysing the patient’s family history and certain breathing tests such as spirometry. Asthma cannot be cured but the disease can be dealt with its proper management. . There are certain marketed drugs that are used in the form of inhalation for managing asthma include inhaled corticosteroids, budesonide, mometasone, ciclesonide, flunisolide and beclomethasone.

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Some of the companies having a pipeline of asthma therapeutics include Regeneron Pharmaceuticals, Inc., Novartis AG, Chiesi Farmaceutici S.p.A., GlaxoSmithKline plc, AstraZeneca plc, Merck Sharp & Dohme Corp., Mundipharma Research Limited, Actavis Inc., Sanofi, AbbVie, Inc., Boehringer Ingelheim GmbH, Genentech, Inc., Rhizen Pharmaceuticals SA.